_{High-resolution 3D imaging of bone microstructure and the related study of bone adaptation, aging, and disease.}

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_{Mechanisms of EGF-medicated signal transduction; EGF-mediated growth inhibition; Breast cancer and communications research.}

_{Regulation of Cell Growth.}

_{Mouse models of reproductive disorders and cancer; genetic and epigenetic regulation.}

_{Regulation of blood vessels in development and disease.}

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_{Development of the vertebrate embryo -- the role of the Rel proto-oncogene in the formation of the nervous system of amphibians.}

_{My research covers various aspects of biomedical imaging for both pre-clinical and clinical applications. Current projects include: automated analysis of medical images and radiation management in x-ray imaging. I offer a course (Med 6106) on diagnostic imaging modalities tailored for biomedical students.}

_{Tier 1 Canada Research Chair in Cell Signaling and Translational Medicine}

_{Development and Cancer to Ocular Health and Aging}

_{microcirculation, oxygen transport, mass transport, blood flow regulation, sepsis, type 2 diabetes, preeclampsia, and inflammation}

_{Alterations in Cell Metabolism in Age- and Mitochondrial-Associated Diseases}

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_{Cellular regulations of electrophysiology and force development of ischemic heart.}

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_{Cardiovascular Pharmacology; Heart Failure; Venous circulation; Receptor kinetics.}

_{Vascular regulatory mechanisms and their significance in cardiovascular and neurological diseases.}

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_{Epigenomic drift mechanisms in cancers and neurodegenerative diseases using integrative omics analytics.}

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_{Immunology of chronic viral infection in relation to aging.}

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_{Virus infection and cellular signaling pathways.}

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_{Understanding the immuno-metabolic signaling within myeloid cells including monocytes and macrophages during multiple sclerosis (MS) pathology, an inflammatory and degenerative condition of the central nervous system}

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_{I have an opportunity to work with various RNA viruses during my post-doctoral training at The Rockefeller University. My research focuses on Virus-Host interaction. I have a particular interest in the Hepatitis C virus (HCV) and characterizing the humoral response to HCV. HCV is a diverse virus divided into many genotypes. An ideal protective humoral response is to induce broadly neutralizing antibodies. My research aims to understand the mechanism of antibody-mediated neutralization and develop ways to generate a broad humoral response, a necessary step toward a prophylactic HCV vaccine.}

_{Molecular Virology of Hepatitis C Virus.}

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_{Regulation of dopamine neurons.}

_{Neurobiology of Obesity; Cancer Neuroscience
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_{Neuroimmunology, inflammation, multiple sclerosis, and glial cell differentiation.
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_{Synaptic neurotransmission and neurodegenerative disease.}

_{Synaptic physiology and pharmacology; G-protein-coupled receptors; psychiatric disorders.}

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_{Neural stem cell biology, neurogenesis, neural regeneration, stroke.}

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_{Mechanisms of learning, memory and memory diseases.}

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Immunoregulation of Thyroid Disease.

_{Regulation and expression of peptide-dependent HLA epitopes in different antigen-presenting cells; HLA epitopes associated with disease susceptibility and resistance.}

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Molecular mechanism of signal transduction during growth factor/oncogene-induced cell differentiation; Identification of early response genes to fibroblast growth factor.

[Neuroscience] A window on promoting memory.

Cellular and molecular mechanisms that are involved in neuronal survival and axonal growth.

Virus-host interactions in immunopathogenesis of liver diseases; molecular biology and immunology of hepatitis B and C virus persistence; immunotherapy of viral hepatitis.

Role of growth factor-related oncogenes in development; Characterization of pattern formation genes.

Alterations in the cerebrovasculature associated with hemorrhagic stroke development; The role of the kidney and renin angiotensin system in the production of hemorrhagic stroke; The role of endothelium in the production of posthemorrhagic vasospasm; The electrophysiological and pharmacological mechanism promoting the autoregulation of cerebrovascular blood flow.

Nervous control of blood pressure; Sympathetic control of renal function; Blood pressure variability; Reflex control of cardiac metabolism.